Board Thread:General Discussion/@comment-65.31.79.34-20140310003509/@comment-86.182.81.218-20140310232729

You shouldn't need anything more than a regular pickaxe to pick up a DSU or any of the other Minefactory Reloaded machines/blocks.

And as long as you have more than one stack of an item in the DSU then the contents shouldn't land on the floor when the DSU is picked up (like they would with a normal chest), they certainly shouldn't 'disappear' completely.